One of these, osteopetrosis (marble bone disease), is more or less the opposite of osteoporosis. Instead of overactive osteoclasts, osteopetrosis results from a variety of genetic defects that impair the ability of osteoclasts to resorb bone.
What causes osteopetrosis?
The X-linked type of osteopetrosis, OL-EDA-ID, results from mutations in the IKBKG gene. In about 30 percent of all cases of osteopetrosis, the cause of the condition is unknown. The genes associated with osteopetrosis are involved in the formation, development, and function of specialized cells called osteoclasts.
What is the male version of osteoporosis?
As many as 2 million American men already have osteoporosis, the bone thinning that makes bones brittle and porous and at likely to fracture. Twelve million men are at risk, and may have early signs of bone loss and low bone density, called osteopenia.
How do you know if you have osteopetrosis?
Osteopetrosis is characterized by overly dense bones throughout the body. Symptoms include fractures, low blood cell production, and loss of cranial nerve function causing blindness, deafness, and/or facial nerve paralysis. Affected individuals may experience frequent infections of teeth and the bone in the jaw.
Who is most likely to get osteopetrosis?
Osteoporosis affects men and women of all races. But white and Asian women, especially older women who are past menopause, are at highest risk. Medications, healthy diet and weight-bearing exercise can help prevent bone loss or strengthen already weak bones.
How can osteopetrosis be prevented?
Get enough calcium and vitamin D and eat a well balanced diet. Engage in regular exercise. Eat foods that are good for bone health, such as fruits and vegetables. Avoid smoking and limit alcohol to 2-3 drinks per day.
Is Osteosclerosis serious?
Osteosclerosis is a disorder that is characterized by abnormal hardening of bone and an elevation in bone density. It may predominantly affect the medullary portion and/or cortex of bone.
What age do bone spurs develop?
Bone spurs are most common in people 60 years or older, but younger people can get them, too. People with osteoarthritis (OA) are much more likely to get bone spurs. OA is a common form of “wear and tear” arthritis that happens when cartilage, which cushions your bones, wears down.
What does osteoporosis pain feel like?
Sudden, severe back pain that gets worse when you are standing or walking with some relief when you lie down. Trouble twisting or bending your body, and pain when you do. Loss of height.