Quick Answer: What is the role of hyperbaric oxygen therapy HBOT in the treatment of refractory osteomyelitis?

A unique mechanism by which HBOT is beneficial in osteomyelitis is in promoting osteoclast function. The resorption of necrotic bone by osteoclasts is oxygen-dependent. This has best been demonstrated in animal models of osteomyelitis.

How does HBOT help osteomyelitis?

Osteomyelitis– Bone Infection

HBOT can help to heal bone disorders by stimulating both the osteoclasts and the osteoblasts. This helps and leads to the re-absorption of dead bone and the creation of new bone.

Can osteomyelitis be treated with hyperbaric oxygen therapy?

Hyperbaric oxygen therapy (HBOT) is associated with remission rates of 81 to 85 percent at two to three years in patients with chronic refractory osteomyelitis.

Is there a role for hyperbaric oxygen therapy in the treatment of refractory wounds of rare etiology?

There was some evidence that HBOT may improve the healing rate of wounds by increasing nitric oxide (NO) levels and the number of endothelial progenitor cells in the wounds. HBOT may also improve pain in these ulcers.

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What is the function of a hyperbaric oxygen treatment?

Hyperbaric oxygen therapy, or HBOT, is a type of treatment used to speed up healing of carbon monoxide poisoning, gangrene, stubborn wounds, and infections in which tissues are starved for oxygen.

What antibiotics are used to treat osteomyelitis?

For osteomyelitis caused by anaerobic gram-negative bacteria, clindamycin, metronidazole, beta-lactam/beta lactamase inhibitor combinations, or carbapenems are the drugs of choice.

How is chronic osteomyelitis treated?

The most common treatments for osteomyelitis are surgery to remove portions of bone that are infected or dead, followed by intravenous antibiotics given in the hospital.


  1. Drain the infected area. …
  2. Remove diseased bone and tissue. …
  3. Restore blood flow to the bone. …
  4. Remove any foreign objects. …
  5. Amputate the limb.

What types of bacterial infections can be treated with hyperbaric oxygen?

HBOT is used as either a primary or adjunctive treatment in the management of infections such as gas gangrene, necrotizing fasciitis, diabetic foot infections, refractory osteomyelitis, neurosurgical infections and fungal infections.

What is chronic osteomyelitis?

Chronic osteomyelitis represents a progressive inflammatory process caused by pathogens, resulting in bone destruction and sequestrum formation. It may present with periods of quiescence of variable duration, whereas its occurrence, type, severity and prognosis is multifactorial.

What does refractory osteomyelitis mean?

Refractory osteomyelitis is defined as a chronic osteomyelitis that persists or recurs after appropriate interventions have been performed or where acute osteomyelitis has not responded to accepted management techniques.

What is the most common complication of hyperbaric oxygen therapy?

Barotrauma is a term that refers to injury due to increased pressure. Barotrauma of the ear is the most frequent complication of HBO. The middle-ear is an air-filled cavity behind the ear drum that connects to the throat through a slit-like passage called the eustachian tube.

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What types of conditions are treated using hyperbaric chambers?

HBOT is used to treat many different health conditions including:

  • Carbon monoxide poisoning.
  • Cyanide poisoning.
  • Injury from crushing.
  • Gas gangrene, a form of gangrene in which gas collects in tissues.
  • Decompression sickness.
  • Sudden or traumatic inadequate blood flow in the arteries.
  • Select wound healing.
  • Skin grafts and flaps.

How will I feel after hyperbaric treatment?

It is normal to feel fatigued after Hyperbaric Oxygen therapy. This is a normal side effect, and should not limit your normal activities. If you feel that it is prolonged excessive fatigue, please notify us. The shape of your eye can temporarily change for up to six weeks following hyperbaric treatments.

How much does hyperbaric treatment cost?

Hard HBOT in a hyperbaric clinic typically costs $250 per session, or $10,000 for 40 sessions. Thus, the standard HBOT protocol costs $20,000 for 80 sessions. Since many people go on to do hundreds ofsessions over a period of years, the costs can be very high.

How many hyperbaric treatments do I need?

Many people feel their best after completing two sessions a day for five days in a row each week. Anyone who needs oxygen therapy for a particularly serious condition should think about committing to at least three sessions a week for the best results. Most people do well with 30 to 40 sessions.

Who is not a candidate for hyperbaric oxygen therapy?

Relative contraindications to evaluate before treatment include, but are not limited to, the following: Uncontrolled hypertension (blood pressure can increase during treatment) Diabetes mellitus with glucose levels greater than 300 or less than 100.

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