What causes osteoporosis at a cellular level?

Osteoporosis is a metabolic bone disease that, on a cellular level, results from osteoclastic bone resorption not compensated by osteoblastic bone formation.

What cell type causes osteoporosis?

Bone homeostasis depends on the resorption of bone by osteoclasts and formation of bone by osteoblasts. Imbalance of this tightly coupled process can cause diseases such as osteoporosis. Thus, the mechanisms that regulate communication between osteoclasts and osteoblasts are critical to bone cell biology.

What type of change in bone cell activity could cause osteoporosis?

In adults, the daily removal of small amounts of bone mineral, a process called resorption, is balanced by an equal deposition of new mineral in order to maintain bone strength. When this balance tips toward excessive resorption, bones weaken and over time can become brittle and prone to fracture (osteoporosis).

What is the best doctor to treat osteoporosis?

A variety of medical specialists treat people with osteoporosis, including internists, gynecologists, family doctors, endocrinologists, rheumatologists, physiatrists, orthopaedists, and geriatricians. There are a number of ways to find a doctor who treats osteoporosis patients.

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What is the most common drug used to treat osteoporosis?

For both men and women at increased risk of fracture, the most widely prescribed osteoporosis medications are bisphosphonates. Examples include: Alendronate (Binosto, Fosamax) Ibandronate (Boniva)

How should you sleep with osteoporosis?

What’s the best sleeping position for osteoporosis of the spine? Sleeping on your side or back are both viewed as suitable for those with brittle bones. You may want to avoid sleeping on your stomach because it can cause too much of an arch in the back, which is both unhealthy and uncomfortable.

What happens if osteoporosis is left untreated?

What can happen if osteoporosis is not treated? Osteoporosis that is not treated can lead to serious bone breaks (fractures), especially in the hip and spine. One in three women is likely to have a fracture caused by osteoporosis in her lifetime. Hip fractures can cause serious pain and disability and require surgery.

Will osteoporosis shorten my life?

The residual life expectancy was 18.2 years for men beginning osteoporosis treatment at age 50 years and 7.5 years for men beginning treatment at age 75 years. The residual life expectancy was 26.4 years and 13.5 years for women who began treatment at ages 50 years and 75 years, respectively.

Which hormone is responsible for osteoporosis?

Parathyroid hormone (PTH) is an important contributor to the bone remodeling process. High levels of PTH can activate osteoclasts and cause excessive bone breakdown. Calcium in your blood triggers the release of PTH.

What can an endocrinologist do for osteoporosis?

Endocrinologists specialize in treating and preventing bone loss and preventing fractures. In addition, endocrinologists treat disorders that may affect bones, such as hyperparathyroidism, low and high levels of calcium. Become familiar with osteoporosis risk factors.

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How can you prevent and manage osteoporosis?

Prevention of osteoporosis

  1. have a healthy and varied diet with plenty of fresh fruit, vegetables and whole grains.
  2. eat calcium-rich foods.
  3. absorb enough vitamin D.
  4. avoid smoking.
  5. limit alcohol consumption.
  6. limit caffeine.
  7. do regular weight-bearing and strength-training activities.

Are bananas good for osteoporosis?

As all these nutrients play an essential role for your health, they also improve your bone density. Eat pineapple, strawberries, oranges, apples, bananas and guavas. All these fruits are loaded with vitamin C, which in turn, strengthen your bones.

What are the two medications that may cause osteoporosis after long term use?

The medications most commonly associated with osteoporosis include phenytoin, phenobarbital, carbamazepine, and primidone. These antiepileptic drugs (AEDs) are all potent inducers of CYP-450 isoenzymes.

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