Eye muscle myositis is an idiopathic inflammation of the extraocular muscles in the absence of thyroid disease, ocular myasthenia gravis, and other systemic, particularly autoimmune mediated diseases, resembling CD4+ T cell-mediated dermatomyositis.
Is extraocular myositis painful?
providing stable results. Orbital myositis is an inflammatory disorder of the extraocular musculature. The common symptoms associated with the disorder are pain during ocular movement, periorbital edema, diplopia, ophthalmoplegia, ptosis, conjunctival ecchymosis, and proptosis.
How is extraocular myositis treated?
Clinical findings, notably exophthalmos secondary to swelling of the extraocular muscles help in the diagnosis of EOM. Treatment encompasses systemic immunosuppressive therapy, typically comprising corticosteroids, azathioprine, and/or cyclosporine.
Can humans get extraocular myositis?
Extraocular myositis is a common feature of Graves disease in humans, an autoimmune condition of the thyroid gland characterised by goitre, exophthalmos, eyelid retraction and areas of ‘orange-peel’ skin, first discovered in 1835 by an Irish doctor from Dublin named Robert James Graves.
What are the symptoms of myositis?
The main symptom of myositis is muscle weakness. The weakness may be noticeable or may only be found with testing. Muscle pain (myalgias) may or may not be present.
Symptoms of Myositis
- Thickening of the skin on the hands.
- Difficulty swallowing.
- Difficulty breathing.
Can myositis affect your eyes?
Ocular myositis describes a rare inflammatory disorder of single or multiple extraocular eye muscles. Unilateral or sequential bilateral subacute painful diplopia is the leading symptom of eye muscle myositis.
Why do my extraocular muscles hurt?
When your eyes are not properly aligned, you may experience double vision, which the brain rejects. To compensate for the misalignment and keep your eyes moving in sync, the extraocular muscles have to work overtime. Eventually, these tiny muscles become strained and fatigued, leading to a range of painful symptoms.
What is myositis?
Myositis means inflammation of the muscles that you use to move your body. An injury, infection, or autoimmune disease can cause it. Two specific kinds are polymyositis and dermatomyositis. Polymyositis causes muscle weakness, usually in the muscles closest to the trunk of your body.
Can eye muscles get sore?
Asthenopia (eye strain) is a feeling that your eyes are tired, sore, or achy. You can feel this way after reading or looking at a computer or phone screen for a long time. This sensation develops due to prolonged use of the muscles that control your eye movements and your pupils (the dark circles of your eyes).
Can myositis cause ptosis?
Orbital myositis should be considered in the differential diagnosis of acquired ptosis even if extraocular movements are full. We hope that the features of the ptosis will be reported in other cases to find out if the ptosis is the result of oedema or if the levator is affected by myositis.
What muscles are affected by polymyositis?
The muscle weakness associated with polymyositis involves the muscles closest to the trunk, such as those in your hips, thighs, shoulders, upper arms and neck. The weakness affects both the left and right sides of your body, and tends to gradually worsen.
Does polymyositis cause eye problems?
Ocular muscles are never involved in generalized polymyositis. However, isolated orbital myositis, an inflammatory disorder involving the extraocular muscles, is well described. Facial and bulbar muscle weakness is extremely rare in individuals with polymyositis.